Mimi Ghosh

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Bio

I grew up in Kolkata, India, where my parents still live. After high school I received a scholarship to a tiny college in West Virginia, and decided to come and see America. Small town West Virginia was a bit of a culture shock after Kolkata which is a lively, bustling, and extremely crowded city. But I settled there for a few years and completed my BS and MS. Afterwards I attended the University of Pittsburgh, School of Public Health, where I completed my PhD in Infectious Diseases and Microbiology. My focus at the University of Pittsburgh was characterizing the immune responses that occur in the brain shortly after HIV infection. This was the beginning of my interests in the HIV/AIDS field. Right after my PhD, I moved to Lebanon, New Hampshire (a very beautiful but very cold place) as a post-doctoral fellow in Dartmouth Medical School and started working in the area of HIV transmission in women. I have always been interested in women's rights and women's health issues; but it is at Dartmouth where my life-time research interests sharpened into focus as I figured out how I can use my scientific training to help protect women from HIV/AIDS. However, protecting women is so much more than laboratory science. Women in many cultures do not have the right to negotiate condom use with their partners and husbands and desperately need women-controlled methods to protect themselves against HIV and other sexually transmitted pathogens. My goal is to utilize my scientific training to help develop such methods that will help and empower women.

When I am not working, I am reading! I am a voracious reader and gobble up just about every topic under the sun. My apartment suffers from a constant overflow of books and many have to be stored in my pantry!

Expertise

Expertise:

HIV/AIDS

Reproductive Health

Women's Health

Immunology

Education:

Bachelor of Science (Molecular Biology/Biotechnology), Salem-Teikyo University, 1995

Master of Science, (Molecular Biology/Biotechnology), Salem-Teikyo University, 1999 (Currently Salem International University)

Doctor of Philosophy (Infectious Diseases and Microbiology), University of Pittsburgh Graduate School of Public Health, 2005

Post-Doctoral Fellowship, Dartmouth Medical School, 2005-2011

Teaching:

Co-Director, Masters of Science in Public Health Microbiology and Emerging Infectious Diseases Program (MS PHMEID)

PubH 6278 Public Health Virology (Course Director)

MICR 8210 Infection and Immunity (Course Co-Director)

Community Service:

Dr. Ghosh is a member of the American Society for Reproductive Immunology, the International AIDS Society and the International Society of Reproductive Immunology. A committed volunteer, she is the Co-founder and Chief Administrative Officer of International Konditi Development Initiative (I-KODI), a non-profit organization that supports basic educational and health-care needs in an impoverished community in rural Kenya where the prevalence of HIV is particularly high. As a member of the Dartmouth College International Students Program, Ghosh taught basic English, American culture and survival skills to international scholars and spouses in the Upper Valley Region in New Hampshire.

Research

Research:

Dr. Ghosh's research interests are broadly focused in the area of reproductive immunology. She studies HIV acquisition/transmission in women, specifically focusing on the mucosal immune responses and hormonal regulation. She is interested in working with vulnerable populations and currently has projects that involve post-menopausal women, adolescent girls, female sex workers and women who have experienced sexual violence. Professor Ghosh is specifically interested in the translational public health aspects of HIV/AIDS that can lead to the development of preventative and therapeutic interventions.

Publications

Publications:

Publications (Last 5 years)

Ghosh M, Jais M, Delisle J, Younes N, Benyeogor I, Biswas R, Mohamed H, Daniels J, Wang C, Young M, Kassaye S. Dysregulation in Genital Tract Soluble Immune Mediators in Postmenopausal Women is Distinct by HIV Status. AIDS Res Hum Retroviruses. 2019 Feb.
Ghosh M, Daniels J, Pyra M, Juzumaite M, Jais M, Murphy K, Taylor TN, Kassaye S, Benning L, Cohen M and Weber K. Impact of chronic sexual abuse and depression on inflammation and wound healing in the female reproductive tract of HIV-uninfected and HIV-infected women. PLoS One. 2018 Jun 12;13(6).
Ghosh M, Jais M, Biswas R, Jarin J, Daniels J, Joy C, Juzumaite M, Emmanuel V, Gomez-Lobo V. Immune biomarkers and anti-HIV activity in the reproductive tract of sexually active and sexually inactive adolescent girls. Am J Reprod Immunol. 2018 Jun;79(6).
Williams B, *Ghosh M, Boucher CAB, Bushman F, Carrington-Lawrence S, Collman RG, Dandekar S, Dang Q, Malaspina A, Paredes R, Wilson CC, Nowak P, Klatt NR, Lagenaur L, Landay AL. A Summary of the Second Annual HIV Microbiome Workshop. AIDS Res Hum Retroviruses. 2017 Dec;33(12):1258-1264.*1st co-author
Aldous A, Magnus M, Roberts A, DeVore H, Moriarty T, Hatch C, Zumer M, Simon G, Ghosh M. Challenges in Conducting Research on Sexual Violence and HIV and Approaches to Overcome Them. Am J Reprod Immunol. 2017 Jul;78(1).
Jais M, Younes N, Chapman S, Cu-Uvin S, Ghosh M. Reduced levels and bioactivity of endogenous protease Cathepsin D in genital tract secretions of postmenopausal women. AIDS Res Hum Retroviruses. 2017 May;33(5):407-409
Jais M, Younes N, Chapman S, Cu-Uvin S, Ghosh M. Reduced Levels of Genital Tract Immune Biomarkers in Postmenopausal Women: Implications for HIV Acquisition. Am J Obstet Gynecol. 2016 Sep;215(3):324.
Patel MV, Ghosh M, Fahey JV, Ochsenbauer C, Rossoll RM, Wira CR. Innate Immunity in the Vagina (Part II): Anti-HIV Activity and Antiviral Content of Human Vaginal Secretions. Am J Reprod Immunol. 2014 Jul, 72(1):22-33.
Ghosh M. Secreted mucosal antimicrobials in the female reproductive tract that are important to consider for HIV prevention. Am J Reprod Immunol. 2014 Jun;71(6):575-88.

Mimi

Ghosh

Associate Professor

Mimi Ghosh

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